Pseudomembranous colitis treatment in India: An Overview

Published: 09th April 2010
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Pseudomembranous colitis treatment in India is now being provided to the patients from all over the world with latest facilities and globally benchmarked healthcare services administered by surgeons and physicians trained in international medical practices. Pseudomembranous colitis treatment in India is provided at hospitals having a team of highly-trained doctors of international repute and research analysts working together to develop newer treatment approaches and using them for effective patient cure and care. With the use of advanced medical technology and newly invented techniques the recovery time after surgery is shortened and within very short period time frame patients becomes fit and return back to work.

What is Pseudomembranous Colitis?

Pseudomembranous colitis, sometimes called antibiotic-associated colitis or C. difficile colitis is an inflammatory condition of the colon that occurs in some people who have received antibiotics. The inflammation in Pseudomembranous colitis is almost always associated with an overgrowth of the bacterium Clostridium difficile (C. difficile), although in rare cases, other organisms can be involved. Pseudomembranous colitis occurs more often in adults than in children, and it's rare in infants because of protective antibodies received from their mothers. The condition can cause you to experience painful, alarming symptoms and can even become life-threatening. However, treatment for most cases of Pseudomembranous colitis is successful.

Symptoms of Pseudomembranous colitis

The most common and the initial sign of pseudomembranous colitis is watery, and sometimes bloody, diarrhea.

• Diarrhea

• Abdominal cramps and pain

• Fever, which may be higher than 101 F (38.3 C)

• Urge to have a bowel movement (fecal urgency)

• Pus or mucus in your stool

• Nausea

• Dehydration

Symptoms of Pseudomembranous colitis can begin within one to two days after you begin receiving an antibiotic, or they may not occur until several weeks after you discontinue the antibiotic.

Pseudomembranous colitis is more common in certain people in hospitals and nursing homes, often when they're receiving drugs or undergoing surgery in which antibiotics are part of the treatment regimen.

Treatments and drugs

Once the diagnosis of Pseudomembranous colitis is made, your doctor will stop the antibiotic that was associated with development of the disorder. Sometimes, this may be enough to resolve your condition, or at least ease signs, such as diarrhea.

If you have severe symptoms and your doctor suspects Pseudomembranous colitis, you may be started on treatment before stool tests confirm the diagnosis. Once you begin treatment for Pseudomembranous colitis, signs and symptoms may begin to improve within a few days, and they often resolve completely within two weeks.

To treat more-severe cases of Pseudomembranous colitis, your doctor will choose from among a number of medications, particularly antibiotics other than the one associated with your illness.

Most common medications

The antibiotic metronidazole (Flagyl) is the first drug of choice for treating disorders associated with C. difficile bacteria. However, recent research suggests that the antibiotic vancomycin (Vancocin) may produce a faster response and may be associated with a lower risk of recurrence. If your condition is severe, your doctor may prescribe vancomycin first because of its rapid response rate. However, vancomycin only works when it's given as a pill. If you are very ill and not eating, your doctor may prescribe intravenous metronidazole.

If you're a pregnant woman in your first trimester, don't take metronidazole because of the risk of birth defects. It's also a poor choice if you're breast-feeding because the drug's effect on babies is unknown. Doctors also generally avoid prescribing this medication in children younger than 10 years old. In certain cases, doctors may give a combination of vancomycin and metronidazole.

Rifaximin (Xifaxan) is another antibiotic that doctors sometimes use to manage pseudomembranous colitis.

The antibiotics used to treat pseudomembranous colitis are usually given by mouth. However, depending on the severity of the inflammation and the medication, you may be treated with these drugs intravenously, via an enema, or through a tube inserted through your nose and threaded into your stomach (nasogastric tube).

Why antibiotics as a treatment?

Antibiotics cause Pseudomembranous colitis because they kill the normal bacteria in your colon and allow toxic C. difficile to grow. Although it may seem strange to use antibiotics to treat a disorder caused by antibiotics, treatment with antibiotics eradicates the C. difficile and allows the normal bacteria to grow back; restoring the balance of bacteria in your colon to what it was before any antibiotics were given.

Dealing with dehydration

If you become dehydrated due to diarrhea, your doctor will prescribe electrolyte solutions to replace lost fluids. At times, these rehydration solutions will be administered intravenously.

Don't take anti-diarrheal medications - such as loperamide (Imodium) or the combination drug diphenoxylate and atropine (Lomotil) - without your doctor's knowledge. These drugs could worsen the signs and symptoms of Pseudomembranous colitis.

When surgery is an option?

If antibiotic treatment doesn't reduce colonic inflammation and ease your symptoms, and your condition worsens, your doctor may recommend intestinal surgery. This is rare, however; surgery is needed in less than 4 percent of people with Pseudomembranous colitis.

Surgery becomes an option in people who have progressive organ failure, rupture of the colon and inflammation of the lining of the abdominal wall (peritonitis). Surgery typically involves removal (resection) of the diseased section of the bowel (subtotal colectomy).

Lifestyle and home remedies

To support your doctor's treatment for Pseudomembranous colitis, several self-help measures may benefit you:

Drink fluids: Drink water and other clear fluids, such as apple juice, tea and bouillon. Fluids with added sodium and potassium (electrolytes) also may be beneficial. Stay away from carbonated beverages, orange juice and other citrus drinks, alcohol, and caffeinated drinks, all of which can make your signs and symptoms worse.

Eat several meals of small portion sizes throughout the day: This is better than eating two or three larger meals because the smaller meals tend to romote more-normal bowel movements.

Eat foods that can help ease diarrhea: These include rice, bananas, plain baked potatoes and toast.

Avoid high-fat, fried or spicy foods: These can worsen your symptoms.

Why India?

Pseudomembranous colitis treatment in India is provided with internationally accredited medical facilities using the latest technologies and highly qualified surgeons and hospital support staff. If you are looking for world-class medical facilities, with no waiting periods, India is the best place to visit. Equipped with state-of-the-art facilities Indian hospitals are proven leaders in providing world-class treatments where some of the most complex surgeries can be done in just a few days, at a fraction of the cost in the Western World. Medical tourism in India is aligned with only the finest health care providers in India facilitating world class medical care travel within India and promises to deliver life changing experiences and unforgettable memories. For more information on Pseudomembranous colitis treatment in India visit us at or mail your queries at or call us at: +91-9371136499, +91- 9860755000 (International) / + 1-415-599-2537 (USA) / +44-20-8133-2571 (UK)

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